In this book,we have selected nine research works at the forefront of molecular and cellular biomechanics to be introduced to our readers.It 1S ouropinion that these works represent the current trend and future directions of cellular biomechanics research.By compiling these different topics into one volume.a unique perspective iS provided on the current state of cell mechanics research and what lies in the future.
- Chapter 1Modeling and Simulations of the Dynamics of Growing Cell Clusters
- 1.1 Introduction
- 1.2 Single cell geometry and kinematics
- 1.2.1 The continuum model
- 1.2.2 The numerical model for the cell geometry
- 1.3 Single cell equilibrium and material model
- 1.3.1 Cell equilibrium
- 1.3.2 The material model
- 1.3.3 Determination of material constants
- 1.4 Modeling cell interactions
- 1.4.1 Cell-to-cell contact
- 1.4.2 Cell-to-cell adhesion
- 1.4.3 Cell-to-cell interaction test
- 1.5 Modeling the cell life cycle
- 1.6 Details of the numerical implementation
- 1.6.1 The finite element model
- 1.6.2 Contact/adhesion interface detection
- 1.6.3 Time integration
- 1.6.4 Parallelization
- 1.7 Numerical results
- 1.8 Summary and conclusions
- References