Jun Ma is an Associate Professor at the Division of Developmental Biology,Cincinnati Children’s Hospital Research Foundation and University of Cincinnati College of Medicine.He graduated from Peking University in 1982,majoring in Biology.He did his graduate work with Mark Ptashne at the Department of Biochemistry and Molecular Biology in Harvard University,and was a Junior Fellow at the Harvard Society of Fellows between 1989-1992.He spent the summer of 1988 in the laboratory of Christiane Nüsslein-Volhard at the Max-Planck-Institute for Developmental Biology in Tübingen to collaborate with Wolfgang Driever.He joined the faculty of the University of Cincinnati College of Medicine in 1992 and has remained there since.Currently he also has a collaborative base at the Institute of Biophysics of the Chinese Academy of Sciences in Beijing.His earlier work on the yeast activator GAL4 helped pave the way to the development of the yeast two-hybrid system.His current research focuses on the mechanisms of transcript on control and development in Drosophila.
- front matter
- Section I The History
- Chapter01 Transcription: The Never Ending Story
- Section II The Machinery
- Chapter02 The General Transcription Machinery and Preinitiation Complex Formation
- Chapter03 The Dynamic Association of RNA Polymerase II with Initiation, Elongation, and RNA Processing Factors during the Transcription Cycle
- Chapter04 General Cofactors：TFIID, Mediator and USA
- Chapter05 Chromatin and Regulation of Gene Expression
- Chapter06 HATs and HDACs
- Chapter07 Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription
- Section III The Regulators
- Chapter08 Transcriptional Activators and Activation Mechanisms
- Chapter09 Transcriptional Repressors and Repression Mechanisms
- Chapter10 STATs in Cytokine-mediated Transcriptional Regulation
- Chapter11 Transcriptional Regulation by Smads
- Chapter12 The Rb and E2F Families of Proteins
- Chapter13 c-Jun：A Complex Tale of a Simple Transcription Factor
- Chapter14 HIV Tat and the Control of Transcriptional Elongation
- Chapter15 Post-translational Modifications of the p53 Transcription Factor
- Chapter16 Actions of Nuclear Receptors
- Chapter17 NFAT and MEF2, Two Families of Calcium-dependent Transcription Regulators
- Chapter18 Hox Genes
- Chapter19 Nuclear Factor-kappa B
- Chapter20 The ATF Transcription Factors in Cellular Adaptive Responses
- Section IV The Genome
- Chapter21 Function and Mechanism of Chromatin Boundaries
- Chapter22 Heterochromatin and X Inactivation
- Chapter23 DNA Methylation Regulates Genomic Imprinting, X Inactivation, and Gene Expression during Mammalian Development
- Chapter24 Comparative Genomics of Tissue Specific Gene Expression
- Chapter25 Transcription and Genomic Integrity
- Chapter26 Cell Death and Transcription
- Section V Special Topics
- Chapter27 Pre-mRNA Splicing in Eukaryotic Cells
- Chapter28 Genome Organization：The Effects of Transcription-driven DNA Supercoiling on Gene Expression Regulation
- Chapter29 The Biogenesis and Function of MicroRNAs
- Chapter30 Transcription Factor Dynamics
- Chapter31 Actin, Actin-Related Proteins and Actin-Binding Proteins in Transcriptional Control
- Chapter32 Wnt Signaling and Transcriptional Regulation
- Chapter33 Regulatory Mechanisms for Floral Organ Identity Specification in Arabidopsis thaliana
- Chapter34 Transcription Control in Bacteria
- Chapter35 Gene Therapy：Back to the Basics
- 版权
