This book offers a comprehensive look into the science ofgene expression and regulation. Focusing on topics such asactions of nuclear receptors, RNA processing, and DNAmethylation and imprinting, Gene Expression andRegulation is edited by a leading biologist and includescontributions by experts in the field.
- Section I The History
- Chapter 01 Transcription: The Never Ending Story
- Section II The Machinery
- Chapter 02 The General Transcription Machinery and Preinitiation Complex Formation
- Chapter 03 The Dynamic Association of RNA Polymerase II with Initiation, Elongation,and RNA Processing Factors during the Transcription Cycle
- Chapter 04 General Cofactors：TFIID, Mediator and USA
- Chapter 05 Chromatin and Regulation of Gene Expression
- Chapter 06 HATs and HDACs 111
- Chapter 07 Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription
- Section III The Regulators
- Chapter 08 Transcriptional Activators and Activation Mechanisms
- Chapter 09 Transcriptional Repressors and Repression Mechanisms
- Chapter 10 STATs in Cytokine-mediated Transcriptional Regulation
- Chapter 11 Transcriptional Regulation by Smads
- Chapter 12 The Rb and E2F Families of Proteins
- Chapter 13 c-Jun：A Complex Tale of a Simple Transcription Factor
- Chapter 14 HIV Tat and the Control of Transcriptional Elongation
- Chapter 15 Post-translational Modifications of the p53 Transcription Factor
- Chapter 16 Actions of Nuclear Receptors
- Chapter 17 NFAT and MEF2, Two Families of Calcium-dependent Transcription Regulators
- Chapter 18 Hox Genes
- Chapter 19 Nuclear Factor-kappa B
- Chapter 20 The ATF Transcription Factors in Cellular Adaptive Responses
- Section IV The Genome
- Chapter 21 Function and Mechanism of Chromatin Boundaries
- Chapter 22 Heterochromatin and X Inactivation
- Chapter 23 DNA Methylation Regulates Genomic Imprinting, X Inactivation, and Gene Expression during Mammalian Development
- Chapter 24 Comparative Genomics of Tissue Specific Gene Expression
- Chapter 25 Transcription and Genomic Integrity
- Chapter 26 Cell Death and Transcription
- Section V Special Topics
- Chapter 27 Pre-mRNA Splicing in Eukaryotic Cells
- Chapter 28 Genome Organization：The Effects of Transcription-driven DNA Supercoiling on Gene Expression Regulation
- Chapter 29 The Biogenesis and Function of MicroRNAs
- Chapter 30 Transcription Factor Dynamics
- Chapter 31 Actin, Actin-Related Proteins and Actin-Binding Proteins in Transcriptional Control
- Chapter 32 Wnt Signaling and Transcriptional Regulation
- Chapter 33 Regulatory Mechanisms for Floral Organ Identity Specification in Arabidopsis thaliana
- Chapter 34 Transcription Control in Bacteria
- Chapter 35 Gene Therapy：Back to the Basics
